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 Field Name  Data Description
Test Name  Everolimus
Code  Everolimus.
CPT Code  80169
Last Modified  
Test Name  Everolimus.
Synonyms  Afinit
Patient Preparation  
Spec. Requirements  Whole Blood
Tube  Lavender (EDTA) or Dark Green (Heparin)
Collection Volume  2.0 mL Lavender or 4.0 mL Green
Storage  Ambient, Refrigerate or Frozen 14 days
Routine TAT  
Days Test Performed  
Performed by BHS  None
See Availability  
Reference Lab  LabCorp of America
Reference Lab Code  700003 Everolimus, Whole Blood
Clinical Use  Everolimus is a proliferation signal inhibitor that prevents allograft rejection. It exerts its immunosuppressive effect by inhibiting the proliferation, and thus clonal expansion, of antigen-activated T cells, which is driven by T-cell-specific interleukins. Everolimus inhibits an intracellular signaling pathway that is triggered up binding of these T-cell growth factors to their respective receptors, and which normally leads to cell proliferation. The blockage of this signal by everolimus leads to an arrest of the cells at the G1 stage of cell cycle.
Reference Range  
Critical Value  
Testing Sample Type  Whole blood
Min Lab Testing Volume  0.5 mL
Special Handling  
Lab Notes  
Methodology  LC/MS-MS - Liquid Chromatography/Tandem Mass Spectrometry

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