| Field Name |
Data Description |
| Test Name |
Luteinizing Hormone (LH) |
| Code |
Luteinizing Hormone., Luteinizing Horm. |
|
CPT Code |
83002 |
| Last Modified |
11/28/2022 1:25:00 PM |
| Test Name |
LH. |
| Synonyms |
Luteinizing Hormone (LH), ICSH, Stimul, Hormon, Inters, Interstitial Cell-Stimulating |
| Patient Preparation |
|
| Spec. Requirements |
Blood |
| Tube |
Red or Gold |
| Collection Volume |
Red 4.0 mL, Gold 3.5 mL, Lithium heparin green 3.0 mL |
| Storage |
Ambient, Refrigerated or Frozen 14 days |
| Routine TAT |
|
| STAT TAT |
N/A |
| Days Test Performed |
|
| Performed by BHS |
None |
| See Availability |
|
| Reference Lab |
LabCorp of America |
| Reference Lab Code |
004283 Luteinizing Hormone (LH) |
| Clinical Use |
The primary clinical use of LH measurement is in evaluating the normalcy of hypothalamic-pituitary-gonadal axis. Measurement of serum gonadotropin levels will allow for distinguishing between primary gonadal failure and deficient gonadal stimulation. LH measurement may also be of clinical importance because growth hormone and LH are frequently the first hormones to be affected by pituitary disease. The serum analysis of LH has also been found to be very useful in the diagnosis and treatment of infertility in women. |
| Reference Range |
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| Critical Value |
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Component |
Male |
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| Testing Sample Type |
Serum or Plasma |
| Min Lab Testing Volume |
1.0 (0.7) mL |
| Special Handling |
This test may exhibit interference when sample is collected from a person who is consuming a supplement with a high doseof biotin (also termed as vitamin B7 or B8, vitamin H, or coenzyme R). It is recommended to ask all patients who may be indicated for this test about biotin supplementation. Patients should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample. |
| Lab Notes |
If red-top tube is used, transfer separated serum to a plastic transport tube. Do not use oxalate, EDTA, or citrate plasma. |
| Methodology |
ECL or ECL - Electrochemiluminescence Immunoassay |
| Limitations |
Secretion of both LH and FSH are pulsatile, in response to the normal intermittent release of gonadotropin releasing hormone (GnRH). In addition, in females both FSH and LH varyover the course of the menstrual cycle, with peaks at time of ovulation. Thus, interpretation of a single determinationmay be difficult. It has been suggested that samples be obtained at 15 to 30 minutes intervals and equal volumes of serum be pooled to decrease the effect of pulsatile secretion. As with all tests containing monoclonal mouse antibodies, erroneous findings may be obtained from samples taken from patients who have been treated with monoclonal mouse antibodies or have received them for diagnostic purposes[1].In rare cases, interference due to extremely high titers of antibodies to streptavidin and ruthenium can occur[1]. The test contains additives, which minimize these effects. |
