| Field Name |
Data Description |
| Test Name |
Zinc, Urine |
| Code |
Zinc.Urine. |
|
CPT Code |
84630, 82570 |
| Last Modified |
7/16/2018 2:01:00 PM |
| Test Name |
Zinc.Urine. |
| Synonyms |
Zn, quantitative 24 hour, 24hr, 24 hr, random |
| Patient Preparation |
|
| Spec. Requirements |
Urine (24 hour or Random) |
| Tube |
24 hour urine container or plastic urine container, no preservative |
| Collection Volume |
5 mL |
| Storage |
Frozen, Refrigerated, Ambient 14 days |
| Routine TAT |
5 days |
| STAT TAT |
|
| Days Test Performed |
Monday - Friday |
| Performed by BHS |
None |
| See Availability |
|
| Reference Lab |
LabCorp of America |
| Reference Lab Code |
003434 Zinc, Urine |
| Clinical Use |
Evaluate zinc exposure; evaluate low serum zinc levels; evaluate compliance in oral zinc therapy of Wilson disease. Low urine zinc levels in the presence of depressed serum zinc tends to confirm zinc deficiency. Zinc poisoning through inhalation of zinc oxide fumes or dust often produces symptoms of respiratory tract irritation, chest pain and cough, fatigue, headache, nausea, fever, and muscle pain. Zinc is utilized as an alloying agent in brass and other metals, as well as in metal plating. Zinc chloride is often produced in the chemical smoke generators that are employed in industry. Zinc chloride is also used in soldering fluxes and wood preservatives. |
| Reference Range |
|
| Critical Value |
|
|
|
| Testing Sample Type |
Urine 24-hour or random |
| Min Lab Testing Volume |
2.0 mL |
| Special Handling |
If 24-hour urine is submitted, then request form must state 24-hour collection volume. Do not use preservative. Preservatives used for routine analysis may contain mercuric oxide (ie, Stabilur), which interferes with all metal testing. |
| Lab Notes |
Instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Screw the lid on securely.
Test includes:Creatinine, urine; zinc, urine; zinc:creatinine ratio; zinc, urine (24-hour) |
| Methodology |
Inductively Coupled Plasma/Mass Spectrometry |
| Limitations |
Zinc deficiency is usually accompanied by decreased urine zinc excretion. Zinc deficiency, however, may be in part due to excess urine losses, especially in cirrhosis, hemolytic anemias, sickle cell disease, alcoholism, diabetes, or chronic renal diseases. |
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