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 Field Name  Data Description
Test Name  Zinc, Urine
Code  Zinc.Urine.
CPT Code  84630, 82570
Last Modified  7/16/2018 2:01:00 PM
Test Name  Zinc.Urine.
Synonyms  Zn, quantitative 24 hour, 24hr, 24 hr, random
Patient Preparation  
Spec. Requirements  Urine (24 hour or Random)
Tube  24 hour urine container or plastic urine container, no preservative
Collection Volume  5 mL
Storage  Frozen, Refrigerated, Ambient 14 days
Routine TAT  5 days
Days Test Performed  Monday - Friday
Performed by BHS  None
See Availability  
Reference Lab  LabCorp of America
Reference Lab Code  003434 Zinc, Urine
Clinical Use  Evaluate zinc exposure; evaluate low serum zinc levels; evaluate compliance in oral zinc therapy of Wilson disease. Low urine zinc levels in the presence of depressed serum zinc tends to confirm zinc deficiency. Zinc poisoning through inhalation of zinc oxide fumes or dust often produces symptoms of respiratory tract irritation, chest pain and cough, fatigue, headache, nausea, fever, and muscle pain. Zinc is utilized as an alloying agent in brass and other metals, as well as in metal plating. Zinc chloride is often produced in the chemical smoke generators that are employed in industry. Zinc chloride is also used in soldering fluxes and wood preservatives.
Reference Range  
Critical Value  
Testing Sample Type  Urine 24-hour or random
Min Lab Testing Volume  2.0 mL
Special Handling  If 24-hour urine is submitted, then request form must state 24-hour collection volume. Do not use preservative. Preservatives used for routine analysis may contain mercuric oxide (ie, Stabilur), which interferes with all metal testing.
Lab Notes  Instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Screw the lid on securely. Test includes:Creatinine, urine; zinc, urine; zinc:creatinine ratio; zinc, urine (24-hour)
Methodology  Inductively Coupled Plasma/Mass Spectrometry
Limitations  Zinc deficiency is usually accompanied by decreased urine zinc excretion. Zinc deficiency, however, may be in part due to excess urine losses, especially in cirrhosis, hemolytic anemias, sickle cell disease, alcoholism, diabetes, or chronic renal diseases.

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